EXPRESSION IN ESCHERICHIA-COLI OF HEPATITIS-B VIRUS-DNA SEQUENCES CLONED IN PLASMID-PBR322

被引：236

作者：

BURRELL, CJ

MACKAY, P

GREENAWAY, PJ

HOFSCHNEIDER, PH

MURRAY, K

机构：

[1] UNIV EDINBURGH, SCH MED, DEPT BACTERIOL, EDINBURGH EH8 9YL, MIDLOTHIAN, SCOTLAND

[2] MICROBIOL RES ESTAB, SALISBURY SP4 0JG, WILTSHIRE, ENGLAND

[3] INST MED & VET SCI, DEPT MOLEC BIOL, ADELAIDE 5000, S AUSTRALIA, AUSTRALIA

来源：

NATURE | 1979年 / 279卷 / 5708期

关键词：

D O I：

10.1038/279043a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Fragments of hepatitis B virus DNA isolated from Dane particles have been inserted into the Escherichia coli plasmid pBR322 and cloned. Cells carrying the hybrid plasmid synthesise antigenic material that reacts specifically with antisera to hepatitis B viral antigens. © 1979 Nature Publishing Group.

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页码：43 / 47

页数：5

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