PITUITARY-HORMONES IN BRAIN - WHERE, HOW, AND WHY

被引：170

作者：

KRIEGER, DT

LIOTTA, AS

机构：

来源：

SCIENCE | 1979年 / 205卷 / 4404期

关键词：

D O I：

10.1126/science.221983

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Peptide and protein hormones usually considered as being of pituitary origin have been detected within the central nervous system by means of radioimmunoassay, bioassay, and immunocytochemical techniques. Intracerebral administration of some of these hormones or fragments thereof elicit behavioral responses, suggesting that they may have a physiological role similar to that described for other peptidergic neurotransmitter or neuromodulator substances. Evidence available for some of these hormones indicates that they are synthesized within the central nervous system and that their regulation may differ from that of their pituitary counterparts. Copyright © 1979 AAAS.

引用

页码：366 / 372

页数：7

共 106 条

[1] APPEARANCE OF BETA-ENDORPHIN-LIKE IMMUNOREACTIVITY IN HUMAN VENTRICULAR CEREBROSPINAL-FLUID UPON ANALGESIC ELECTRICAL-STIMULATION [J].