IN VIVO STUDIES OF [ME-3H]CHOLINE AND [1,2-14C2]CHOLINE INCORPORATION INTO LUNG AND LIVER LECITHINS

被引：38

作者：

SPITZER, HL

NORMAN, JR

MORRISON, K

机构：

[1] Department of Medicine, Pulmonary Division, The University of Alabama Medical Center, Birmingham, Ala

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1969年 / 176卷 / 03期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

D O I：

10.1016/0005-2760(69)90224-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A comparison has been made of [Me-3H]choline and [1,2-14C2]choline incorporation in vivo into the lecithins and the sphingomyelin of lung and liver. The data obtained suggest that in liver, but not in lung, (a) there is significant reincoporation of choline methyl groups into arachidonoyllecithin; (b) there is choline incorporation into linoleoyllecithin not involving CDP-choline; (c) and a disproportionate amount of the choline incorporated into sphingomyelin is endogenously synthesized and not derived from the free choline pool. © 1969.

引用

页码：584 / &

共 19 条

[1]

BALINT JA, 1967, J LIPID RES, V8, P486

[2]

BJORNSTAD P, 1966, J LIPID RES, V7, P38

[3] STUDIES IN PHOSPHOLIPID METABOLISM .2. INCORPORPORATION OF METABOLIC PRECURSORS OF PHOSPHOLIDS IN CHOLINE DEFICIENCY [J].