REGULATORY FUNCTIONS OF THE LAMBDA-REPRESSOR RESIDE IN THE AMINO-TERMINAL DOMAIN

被引:135
作者
SAUER, RT [1 ]
PABO, CO [1 ]
MEYER, BJ [1 ]
PTASHNE, M [1 ]
BACKMAN, KC [1 ]
机构
[1] UNIV CALIF SAN FRANCISCO,DEPT BIOCHEM,SAN FRANCISCO,CA 94143
关键词
D O I
10.1038/279396a0
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The repressor of bacteriophage λis a protein containing two domains of approximately equal size. Fragments containing the amino-terminal domain of repressor bind specifically to λoperator DNA and mediate positive and negative control of λtranscription both in vitro and in vivo. © 1979 Nature Publishing Group.
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页码:396 / 400
页数:5
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