STRUCTURE OF THE REPRESSOR OPERATOR COMPLEX OF BACTERIOPHAGE 434

被引：352

作者：

ANDERSON, JE ^{[1
]}

PTASHNE, M ^{[1
]}

HARRISON, SC ^{[1
]}

机构：

[1] HARVARD UNIV,DEPT BIOCHEM & MOLEC BIOL,CAMBRIDGE,MA 02138

来源：

NATURE | 1987年 / 326卷 / 6116期

关键词：

D O I：

10.1038/326846a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The crystal structure of a specific complex between the DNA-binding domain of phage 434 represser and a synthetic 434 operator DNA shows interactions that determine sequence-dependent affinity. The represser recognizes its operators by its complementarity to a particular DNA conformation as well as by direct interaction with base pairs in the major groove. © 1987 Nature Publishing Group.

引用

页码：846 / 852

页数：7

共 36 条

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