EPIDERMAL GROWTH-FACTOR - INTERACTIONS WITH CELLULAR RECEPTORS

被引：10

作者：

HAIGLER, HT

COHEN, S

机构：

[1] Department of Biochemistry, Vanderbilt University, School of Medicine, Nashville

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1979年 / 4卷 / 06期

关键词：

D O I：

10.1016/0968-0004(79)90444-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Epidermal growth factor (EGF) is a polypeptide hormone isolated from both man and mouse. EGF promotes the growth of epidermis in animals and of many cell types in culture. It has been possible to trace its binding, internalization and degradation in responsive cells and to begin to understand the molecular events associated with the mitogenic activity of this hormone. © 1979.

引用

页码：132 / 134

页数：3

共 20 条

[1]

AHARONOV A, 1978, J BIOL CHEM, V253, P3970

[2]

CARPENTER G, 1975, J BIOL CHEM, V250, P4297

[3] I125 LABELED HUMAN EPIDERMAL GROWTH-FACTOR - BINDING, INTERNALIZATION, AND DEGRADATION IN HUMAN FIBROBLASTS [J].