N-ALPHA-ARYLSULFONYL-OMEGA-(4-AMIDINOPHENYL)-ALPHA-AMINOALKYLCARBOXYLIC ACID-AMIDES - NOVEL SELECTIVE INHIBITORS OF THROMBIN

被引：58

作者：

MARKWARDT, F ^{[1
]}

WAGNER, G ^{[1
]}

STURZEBECHER, J ^{[1
]}

WALSMANN, P ^{[1
]}

机构：

[1] KARL MARX UNIV, DEPT PHARMACEUT CHEM, BIOSCI SECT, DDR-701 LEIPZIG, GER DEM REP

来源：

THROMBOSIS RESEARCH | 1980年 / 17卷 / 3-4期

关键词：

D O I：

10.1016/0049-3848(80)90077-8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：425 / 431

页数：7

共 12 条

[1] THE DETERMINATION OF ENZYME INHIBITOR CONSTANTS [J].

DIXON, M .

BIOCHEMICAL JOURNAL, 1953, 55 (01) :170-171

[2]

GERATZ JD, 1977, CHEM BIOL THROMBIN, P179

[3]

HABERMANN E, 1966, BIOCHEM Z, V346, P133

[4] INTERACTION OF ALPHA-N-(PARA-TOLUENESULPHONYL)-PARA-GUANIDINO-L-PHENYLALANINE METHYL-ESTER WITH THROMBIN AND TRYPSIN [J].

KLAUSNER, YS ;

RIGBI, M ;

TICHO, T ;

DEJONG, PJ ;

NEGINSKY, EJ ;

RINOTT, Y .

BIOCHEMICAL JOURNAL, 1978, 169 (01) :157-167

[5]

MARKWARDT F, 1973, PHARMAZIE, V28, P326

[6]

MARKWARDT F, 1974, HAEMOSTASIS, V3, P185

[7] NEW SERIES OF SYNTHETIC THROMBIN-INHIBITORS (OM-INHIBITORS) HAVING EXTREMELY POTENT AND SELECTIVE ACTION [J].

OKAMOTO, S ;

HIJIKATA, A ;

IKEZAWA, K ;

KINJO, K ;

KIKUMOTO, R ;

TONOMURA, S ;

TAMAO, Y .

THROMBOSIS RESEARCH, 1976, 8 :77-82

[8]

STURZEBECHER J, 1978, PHARMAZIE, V33, P599

[9]

STURZEBECHER J, 1976, ACTA BIOL MED GER, V35, P1665

[10] SYNTHETIC INHIBITORS OF SERINE PROTEINASES .14. INHIBITION OF FACTOR XA BY DERIVATIVES OF BENZAMIDINE [J].

STURZEBECHER, J ;

MARKWARDT, F ;

WALSMANN, P .

THROMBOSIS RESEARCH, 1976, 9 (06) :637-646

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