IMMUNOCHEMICAL STUDIES ON COLLAGEN .1. BINDING AND PRECIPITATION OF GUINEA-PIG SKIN COLLAGEN AND GELATIN WITH RABBIT ANTI-COLLAGEN

被引：8

作者：

MICHAELI, D

KAMENECKA, H

BENJAMINI, E

KETTMAN, JR

LEUNG, DYK

MINER, RC

机构：

来源：

IMMUNOCHEMISTRY | 1968年 / 5卷 / 05期

关键词：

D O I：

10.1016/0019-2791(68)90180-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The conditions required for the formation of precipitin between guinea-pig collagen and rabbit antibodies were investigated. The amount of precipitin was found to be inversely related to the ionic strength of the solution and, to a lesser extent, inversely related to temperature. Gelatin, the heat-denatured form of collagen, could also form precipitins with anti-collagen, suggesting that the quaternary and tertiary structures of collagen played little or no role in the recognition and binding with the anti-collagen sera used. © 1968.

引用

页码：433 / +

页数：1

共 18 条

[1] STUDIES ON THE CHEMICAL BASIS OF THE ANTIGENICITY OF PROTEINS .2. ANTIGENIC SPECIFICITY OF POLYTYROSYL GELATINS [J].