METHAPYRILENE - DNA AS A POSSIBLE TARGET

被引:6
作者
ROSENKRANZ, HS
KLOPMAN, G
机构
[1] CASE WESTERN RESERVE UNIV,DEPT ENVIRONM HLTH SCI,CLEVELAND,OH 44106
[2] CASE WESTERN RESERVE UNIV,DEPT CHEM,CLEVELAND,OH 44106
来源
MUTATION RESEARCH | 1990年 / 245卷 / 04期
关键词
DNA reactivity; Methapyrilene; Pyrilamine;
D O I
10.1016/0165-7992(90)90152-A
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The structural features contributing to the potential carcinogenicity, DNA-reactivity and genotoxicity of methapyrilene and its non-carcinogenic congener pyrilamine were examined. The analyses suggest that the former has the potential for DNA-reactivity, a property which is absent from the latter. © 1990.
引用
收藏
页码:239 / 243
页数:5
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