REQUIREMENT FOR HSP70 IN THE MITOCHONDRIAL MATRIX FOR TRANSLOCATION AND FOLDING OF PRECURSOR PROTEINS

被引：624

作者：

KANG, PJ ^{[1
]}

OSTERMANN, J ^{[1
]}

SHILLING, J ^{[1
]}

NEUPERT, W ^{[1
]}

CRAIG, EA ^{[1
]}

PFANNER, N ^{[1
]}

机构：

[1] UNIV MUNICH,INST PHYSIOL CHEM,W-8000 MUNICH 2,GERMANY

来源：

NATURE | 1990年 / 348卷 / 6297期

关键词：

D O I：

10.1038/348137a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

By analysis of a temperature-sensitive yeast mutant, a heat-shock protein in the matrix of mitochondria, mitochondrial hsp70 (Ssc1p), is found to be involved both in translocation of nuclear-encoded precursor proteins across the mitochondrial membranes and in (re)folding of imported proteins in the matrix. © 1990 Nature Publishing Group.

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页码：137 / 143

页数：7

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