CARDIAC-SURGERY IN THE OCTOGENARIAN - PERIOPERATIVE OUTCOME AND CLINICAL FOLLOW-UP

被引:131
作者
FREEMAN, WK [1 ]
SCHAFF, HV [1 ]
OBRIEN, PC [1 ]
ORSZULAK, TA [1 ]
NAESSENS, JM [1 ]
TAJIK, AJ [1 ]
机构
[1] MAYO CLIN & MAYO FDN,DEPT BIOSTAT,DIV ANIM & DAIRY SCI,ROCHESTER,MN 55905
关键词
D O I
10.1016/S0735-1097(10)80212-8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The perioperative and follow-up results of cardiac operations employing extracorporeal circulation and cold cardioplegic arrest were examined in 191 consecutive patients greater-than-or-equal-to 80 years of age having surgery over a 5 year period (1982 to 1986). Most patients had severe preoperative symptoms with functional class III (39.8%) or IV (57.1%) limitation. The overall 30 day postoperative cardiac mortality rate was 15.7%. The total in-hospital mortality rate was 18.8%; the mean postoperative hospital stay was 16.4 +/- 13.3 days. The perioperative mortality rate for elective operations was as follows: coronary artery bypass (5.6%), aortic valve replacement (9.6%), aortic valve replacement with coronary bypass (17.9%) and mitral valve surgery with or without coronary bypass (21.4%). Urgent operations were performed in 39 patients (20.4%) with a total perioperative mortality rate of 35.9%; urgent coronary artery bypass was performed in 26 patients (67%) with an in-hospital mortality rate of 23.1%. Clinical evidence of left ventricular failure, functional class IV symptoms, left ventricular ejection fraction < 50%, mitral valve repair or replacement for severe mitral regurgitation and urgent operation were associated with an increased perioperative mortality rate. Follow-up study in all 155 patients surviving postoperative hospitalization at 22.6 +/- 14.8 months showed significant improvement in symptom status in all surgical subgroups. There were 18 follow-up deaths (11.6%); 10 were noncardiac. The actuarial survival rate of the entire study group was significantly better than that in age- and gender-matched control subjects (p = 0.037). Elective cardiac surgery can be performed in selected octogenarians without a prohibitive mortality rate and with significant lessening of symptoms and possibly, overall improvement in longevity of patients surviving postoperative hospitalization.
引用
收藏
页码:29 / 35
页数:7
相关论文
共 27 条
[1]   BENEFIT AND COST-ANALYSIS IN GERIATRIC CARE - TURNING AGE-DISCRIMINATION INTO HEALTH-POLICY [J].
AVORN, J .
NEW ENGLAND JOURNAL OF MEDICINE, 1984, 310 (20) :1294-1301
[2]  
COSGROVE DM, 1984, J THORAC CARDIOV SUR, V88, P673
[3]  
CRAVER JM, 1988, CIRCULATION, V78, P85
[4]   CLINICAL, HEMODYNAMIC, AND OPERATIVE DESCRIPTORS AFFECTING OUTCOME OF AORTIC-VALVE REPLACEMENT IN ELDERLY VERSUS YOUNG-PATIENTS [J].
CRAVER, JM ;
GOLDSTEIN, J ;
JONES, EL ;
KNAPP, WA ;
HATCHER, CR .
ANNALS OF SURGERY, 1984, 199 (06) :733-741
[5]  
CZER LSC, 1984, CIRCULATION, V70, P198
[6]   SOCIOPOLITICAL AND ETHICAL CONSIDERATIONS IN THE TREATMENT OF CARDIOVASCULAR-DISEASE IN THE ELDERLY [J].
DUSTAN, HP ;
HAMILTON, MP ;
MCCULLOUGH, L .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1987, 10 (02) :A14-A17
[7]   OPEN-HEART SURGERY IN OCTOGENARIANS [J].
EDMUNDS, LH ;
STEPHENSON, LW ;
EDIE, RN ;
RATCLIFFE, MB .
NEW ENGLAND JOURNAL OF MEDICINE, 1988, 319 (03) :131-136
[8]   VALVE-REPLACEMENT IN THE OCTOGENARIAN [J].
FIORE, AC ;
NAUNHEIM, KS ;
BARNER, HB ;
PENNINGTON, DG ;
MCBRIDE, LR ;
KAISER, GC ;
WILLMAN, VL .
ANNALS OF THORACIC SURGERY, 1989, 48 (01) :104-108
[9]  
FREMES SE, 1989, CIRCULATION, V80, P77
[10]   CORONARY ARTERIOGRAPHY AND CORONARY-ARTERY BYPASS-SURGERY - MORBIDITY AND MORTALITY IN PATIENTS AGES 65 YEARS OR OLDER - A REPORT FROM THE CORONARY-ARTERY SURGERY STUDY [J].
GERSH, BJ ;
KRONMAL, RA ;
FRYE, RL ;
SCHAFF, HV ;
RYAN, TJ ;
GOSSELIN, AJ ;
KAISER, GC ;
KILLIP, T .
CIRCULATION, 1983, 67 (03) :483-491