DELAYED-HYPERSENSITIVITY IN MAN - EFFECTS OF SYSTEMIC ANTICOAGULATION

被引：123

作者：

EDWARDS, RL ^{[1
]}

RICKLES, FR ^{[1
]}

机构：

[1] VET ADM HOSP,NEWINGTON,CT 06111

来源：

SCIENCE | 1978年 / 200卷 / 4341期

关键词：

D O I：

10.1126/science.644314

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Skin test reactivity, lymphocyte transformation, and mononuclear cell tissue factor generation were evaluated both before and during systemic anticoagulation in 24 volunteers. Anticoagulation with warfarin decreased skin test induration and tissue factor generation, but lymphocyte transformation remained unchanged. An intact coagulation mechanism, including tissue factor generation, appears to be important for the development of skin test induration in humans. Copyright © 1978 AAAS.

引用

页码：541 / 543

页数：3

共 36 条

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[2] IN-VITRO EFFECT OF SODIUM WARFARIN ON DNA AND RNA-SYNTHESIS OF MOUSE L1210 LEUKEMIC-CELLS AND WALKER TUMOR-CELLS [J].