CONDITIONED PLACE PREFERENCE PRODUCED BY INFUSION OF MET-ENKEPHALIN INTO THE MEDIAL PREOPTIC AREA

被引：45

作者：

AGMO, A

GOMEZ, M

机构：

[1] Department of Psychology, Universidad Anáhuac, Mexico City

来源：

BRAIN RESEARCH | 1991年 / 550卷 / 02期

关键词：

CONDITIONED PLACE PREFERENCE; REWARD; OPIOID; MET-ENKEPHALIN; MEDIAL PREOPTIC AREA;

D O I：

10.1016/0006-8993(91)91339-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The conditioned place preference procedure was used to evaluate the rewarding properties of D-Ala2-Met5-enkephalinamide (DALA) after bilateral infusion into the medial preoptic area. Doses of 60, 250 and 1000 ng/cannula were used. It was found that all doses of DALA produced place preference. This suggests that the medial preoptic area is a structure where opioid reward is produced in doses as low as those required in already established reward systems. The significance of this in relation to sexual reward is discussed.

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页码：343 / 346

页数：4

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