RETINOIC ACID AND PATTERN-FORMATION IN VERTEBRATES

被引：176

作者：

CONLON, RA

机构：

[1] Department of Genetics, Case Western Reserve University, Cleveland, OH 44106-4955

来源：

TRENDS IN GENETICS | 1995年 / 11卷 / 08期

关键词：

D O I：

10.1016/S0168-9525(00)89089-7

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Retinoic acid has spectacular teratogenic effects on the development of vertebrate embryos, but whether this has significance for the normal mechanisms of development remains an open question. Recent results from the analyses of Hox gene regulation and the phenotypes of mice mutant for the components of the retinoid signaling pathway suggest that retinoic acid is involved is tbe genesis of pattern in vivo.

引用

页码：314 / 319

页数：6

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