IMMUNE-REACTIONS IN DROSOPHILA AND OTHER INSECTS - A MODEL FOR INNATE IMMUNITY

被引：382

作者：

HULTMARK, D

机构：

[1] Department of Molecular Biology, Stockholm University

来源：

TRENDS IN GENETICS | 1993年 / 9卷 / 05期

关键词：

D O I：

10.1016/0168-9525(93)90165-E

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

All insects defend themselves against bacteria and parasites, using cellular and humoral systems that are rapidly activated in infected animals. Among the induced effector molecules are antibacterial proteins and peptides such as cecropins, attacins, lysozymes and insect defensins, the genes for many of which have now been cloned. The induction of this system, which lacks clonally selected receptors like those of vertebrate B and T cells, may provide a model for innate immune reactions in other animals, including vertebrates.

引用

页码：178 / 183

页数：6

共 42 条

[1]

Ashida M., 1990, P239

[2] THE BETA-1,3-GLUCAN-BINDING PROTEIN FROM THE CRAYFISH PACIFASTACUS-LENIUSCULUS, WHEN REACTED WITH A BETA-1,3-GLUCAN, INDUCES SPREADING AND DEGRANULATION OF CRAYFISH GRANULAR CELLS [J].