MASS FRAGMENTOGRAPHIC ASSAY OF 3-METHOXYTYRAMINE IN RAT-BRAIN

被引：45

作者：

GALLI, CL

CATTABENI, F

EROS, T

SPANO, PF

ALGERI, S

DIGIULIO, A

GROPPETTI, A

机构：

[1] UNIV MILAN, INST PHARMACOL & PHARMACOGNOSY, I-20129 MILAN, ITALY

[2] IST RICERCHE FARMACOL MARIO NEGRI, I-20157 MILAN, ITALY

[3] UNIV MILAN, SCH MED, INST PHARMACOL, CHAIR 2, I-20129 MILAN, ITALY

来源：

JOURNAL OF NEUROCHEMISTRY | 1976年 / 27卷 / 03期

关键词：

D O I：

10.1111/j.1471-4159.1976.tb10410.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A mass fragmentographic method for the measurement of 3-methoxytyramine, a metabolite of dopamine formed after its neuronal release, was described. This method allowed the assay of this dopamine metabolite in the picogram range, thus utilizing only few milligrams of brain areas containing dopaminergic neurons. The method was simple and possessed the high specificity intrinsic to mass fragmentography.

引用

页码：795 / 798

页数：4

共 9 条

[1] GAS CHROMATOGRAPHY OF CATECHOLAMINE METABOLITES USING ELECTRON CAPTURE DETECTION AND MASS SPECTROMETRY [J].