Dexamethasone as Treatment in Cerebrovascular Disease. 2. A Controlled Study in Acute Cerebral Infarction

Fifty-four patients with acute cerebral infarction were included in a double-blind study to evaluate Decadron as therapy, When comparison of patients with similar levels of consciousness was made, there was no significant difference between those patients receiving Decadron and those receiving placebo therapy, Three patients developed gastrointestinal tract bleeding in the placebo group, but there were none in the Decadron (R)-treated group. There was no good correlation between the clinical state of the patient and the CSF pressure, either on admission or during the 14-day course of the study.