RNA POLYMERASE-III TRANSCRIPTIONAL UNITS ARE INTERSPERSED AMONG HUMAN NON-ALPHA-GLOBIN GENES

被引：147

作者：

DUNCAN, C

BIRO, PA

CHOUDARY, PV

ELDER, JT

WANG, RRC

FORGET, BG

DERIEL, JK

WEISSMAN, SM

机构：

[1] YALE UNIV, SCH MED, DEPT INTERNAL MED, NEW HAVEN, CT 06510 USA

[2] YALE UNIV, SCH MED, DEPT MOLEC BIOPHYS & BIOCHEM, NEW HAVEN, CT 06510 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1979年 / 76卷 / 10期

关键词：

D O I：

10.1073/pnas.76.10.5095

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Cloned human DNA fragments containing globin genes are transcribed in vitro to form discrete RNA species. One transcription unit is located approximately 1500 base pairs upstream from the G-gamma-globin gene. This transcript is partially homologous to a polymerase III template located approximately 1000 base pairs upstream from the delta-globin gene and to DNA located a short distance downstream from the beta-globin gene.

引用

页码：5095 / 5099

页数：5

共 29 条

[1]

BROWNLEE GG, 1972, DETERMINATION SEQUEN

[2]

BUNN HF, 1977, HUMAN HEMOGLOBINS, P101

[3] SUPERCOILED CIRCULAR DNA-PROTEIN COMPLEX IN ESCHERICHIA COLI - PURIFICATION AND INDUCED CONVERSION TO AN OPEN CIRCULAR DNA FORM [J].