CATALYTIC CYCLOPHANES .5. CATALYTIC CYCLOPHANES - A PORPHYRIN-BRIDGED CYCLOPHANE AS A MODEL FOR CYTOCHROME-P-450 ENZYMES

被引：43

作者：

BENSON, DR ^{[1
]}

VALENTEKOVICH, R ^{[1
]}

DIEDERICH, F ^{[1
]}

机构：

[1] UNIV CALIF LOS ANGELES,DEPT CHEM & BIOCHEM,LOS ANGELES,CA 90024

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1990年 / 29卷 / 02期

关键词：

D O I：

10.1002/anie.199001911

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The porphyrin‐bridged cyclophane 1 was prepared in order to mimic monooxygenase activity and serve as a supramolecular catalyst for the hydroxylation of polycyclic arenes. In methanol, arenes such as anthracene, ace‐naphthylene, and phenanthrene are firmiy complexed in the nonpolar interior of 1. In 2,2,2‐trifluoroethanol in the presence of iodobenzene, the iron(III) derivative 2 catalyzes the oxidation of acenaphthylene to ace‐naphthen‐1‐one (65% yield). (Figure Presented.) Copyright © 1990 by VCH Verlagsgesellschaft mbH, Germany

引用

页码：191 / 193

页数：3

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