INHIBITION OF TUMOR-CELL GROWTH BY INTERFERON-GAMMA IS MEDIATED BY 2 DISTINCT MECHANISMS DEPENDENT UPON OXYGEN-TENSION - INDUCTION OF TRYPTOPHAN DEGRADATION AND DEPLETION OF INTRACELLULAR NICOTINAMIDE ADENINE-DINUCLEOTIDE

被引：103

作者：

AUNE, TM ^{[1
]}

POGUE, SL ^{[1
]}

机构：

[1] GENENTECH INC, DEPT MOLEC IMMUNOL, SAN FRANCISCO, CA 94080 USA

来源：

JOURNAL OF CLINICAL INVESTIGATION | 1989年 / 84卷 / 03期

关键词：

D O I：

10.1172/JCI114247

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页码：863 / 875

页数：13

共 50 条

[1]

AEBI H, 1984, METHOD ENZYMOL, V105, P121

[2] EFFECTS OF ALTERED [ADP-RIBOSE]N METABOLISM ON EXPRESSION OF FETAL FUNCTIONS BY ADULT HEPATOCYTES [J].

ALTHAUS, FR ;

LAWRENCE, SD ;

HE, YZ ;

SATTLER, GL ;

TSUKADA, Y ;

PITOT, HC .

NATURE, 1982, 300 (5890) :366-368

[3]

ALTHAUS FR, 1982, J BIOL CHEM, V257, P5528

[4]

ARRICK BA, 1984, CANCER RES, V44, P4224

[5]

ARRICK BA, 1982, J BIOL CHEM, V257, P1231

[6] SYMPOSIUM - CELLULAR-RESPONSE TO DNA DAMAGE - THE ROLE OF POLY(ADP-RIBOSE) - POLY(ADP-RIBOSE) IN THE CELLULAR-RESPONSE TO DNA DAMAGE [J].

BERGER, NA .

RADIATION RESEARCH, 1985, 101 (01) :4-15

[7] METABOLIC CONSEQUENCES OF DNA DAMAGE - DNA DAMAGE INDUCED ALTERATIONS IN GLUCOSE-METABOLISM BY ACTIVATION OF POLY(ADP-RIBOSE) POLYMERASE [J].

BERGER, SJ ;

SUDAR, DC ;

BERGER, NA .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1986, 134 (01) :227-232

[8] INTERFERONS - FROM VIRUS INHIBITOR TO MODULATOR OF AMINO-ACID AND LIPID-METABOLISM [J].

BORDEN, EC ;

ROSENZWEIG, IB ;

BYRNE, GI .

JOURNAL OF INTERFERON RESEARCH, 1987, 7 (05) :591-596

[9]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

[10] INDUCTION OF TRYPTOPHAN DEGRADATION INVITRO AND INVIVO - A GAMMA-INTERFERON-STIMULATED ACTIVITY [J].

BYRNE, GI ;

LEHMANN, LK ;

KIRSCHBAUM, JG ;

BORDEN, EC ;

LEE, CM ;

BROWN, RR .

JOURNAL OF INTERFERON RESEARCH, 1986, 6 (04) :389-396

← 1 2 3 4 5 →