A NOVEL METALLOPROTEINASE ORIGINALLY ISOLATED FROM BRAIN MYELIN MEMBRANES IS PRESENT IN MANY TISSUES

被引：17

作者：

CHANTRY, A ^{[1
]}

GLYNN, P ^{[1
]}

机构：

[1] INST NEUROL,DEPT NEUROCHEM,LONDON WC1N 1PJ,ENGLAND

来源：

BIOCHEMICAL JOURNAL | 1990年 / 268卷 / 01期

关键词：

D O I：

10.1042/bj2680245

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A monoclonal antibody, CG4, was raised to a novel 60 kDa metalloproteinase purified from a bovine brain myelin glycoprotein fraction. Glycoproteins extracted from both myelin and nine different bovine tissues showed the 60 kDa CG4-immunoreactive band by immunoblotting in amounts that broadly paralleled enzymic activity of this metalloproteinase and varied relatively little among the tissues.

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页码：245 / 248

页数：4

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