ANTIATHEROGENIC EFFECT OF PROBUCOL UNRELATED TO ITS HYPOCHOLESTEROLEMIC EFFECT - EVIDENCE THAT ANTIOXIDANTS INVIVO CAN SELECTIVELY INHIBIT LOW-DENSITY-LIPOPROTEIN DEGRADATION IN MACROPHAGE-RICH FATTY STREAKS AND SLOW THE PROGRESSION OF ATHEROSCLEROSIS IN THE WATANABE HERITABLE HYPERLIPIDEMIC RABBIT

被引：1055

作者：

CAREW, TE

SCHWENKE, DC

STEINBERG, D

机构：

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1987年 / 84卷 / 21期

关键词：

D O I：

10.1073/pnas.84.21.7725

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：7725 / 7729

页数：5

共 26 条

[1] MEASUREMENT INVIVO OF IRREVERSIBLE DEGRADATION OF LOW-DENSITY LIPOPROTEIN IN THE RABBIT AORTA - PREDOMINANCE OF INTIMAL DEGRADATION [J].

CAREW, TE ;

PITTMAN, RC ;

MARCHAND, ER ;

STEINBERG, D .

ARTERIOSCLEROSIS, 1984, 4 (03) :214-224

[2]

DIXON WJ, 1985, BMDP STATISTICAL SOF

[3]

FOLCH J, 1957, J BIOL CHEM, V226, P497

[4]

FOWLER S, 1979, LAB INVEST, V41, P372

[5]

GLAVIND J, 1952, ACTA PATHOL MICROBIO, V17, P347

[6] BINDING-SITE ON MACROPHAGES THAT MEDIATES UPTAKE AND DEGRADATION OF ACETYLATED LOW-DENSITY LIPOPROTEIN, PRODUCING MASSIVE CHOLESTEROL DEPOSITION [J].

GOLDSTEIN, JL ;

HO, YK ;

BASU, SK ;

BROWN, MS .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1979, 76 (01) :333-337

[7] DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM [J].

HAVEL, RJ ;

EDER, HA ;

BRAGDON, JH .

JOURNAL OF CLINICAL INVESTIGATION, 1955, 34 (09) :1345-1353

[8] SUPEROXIDE-MEDIATED MODIFICATION OF LOW-DENSITY-LIPOPROTEIN BY ARTERIAL SMOOTH-MUSCLE CELLS [J].

HEINECKE, JW ;

BAKER, L ;

ROSEN, H ;

CHAIT, A .

JOURNAL OF CLINICAL INVESTIGATION, 1986, 77 (03) :757-761

[9] ENHANCED MACROPHAGE DEGRADATION OF LOW-DENSITY LIPOPROTEIN PREVIOUSLY INCUBATED WITH CULTURED ENDOTHELIAL-CELLS - RECOGNITION BY RECEPTORS FOR ACETYLATED LOW-DENSITY LIPOPROTEINS [J].

HENRIKSEN, T ;

MAHONEY, EM ;

STEINBERG, D .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (10) :6499-6503

[10] PROBUCOL PREVENTS THE PROGRESSION OF ATHEROSCLEROSIS IN WATANABE HERITABLE HYPERLIPIDEMIC RABBIT, AN ANIMAL-MODEL FOR FAMILIAL HYPERCHOLESTEROLEMIA [J].

KITA, T ;

NAGANO, Y ;

YOKODE, M ;

ISHII, K ;

KUME, N ;

OOSHIMA, A ;

YOSHIDA, H ;

KAWAI, C .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (16) :5928-5931

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