OKADAIC ACID - A NEW PROBE FOR THE STUDY OF CELLULAR-REGULATION

被引：1450

作者：

COHEN, P

HOLMES, CFB

TSUKITANI, Y

机构：

[1] FUJISAWA CHEM CO,TOKYO,JAPAN

[2] NATL RES COUNCIL CANADA,MONTREAL,QUEBEC,CANADA

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1990年 / 15卷 / 03期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/0968-0004(90)90192-E

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The tumour promoter okadaic acid is a potent and specific inhibitor of protein phosphatases 1 and 2A. Here we review recent studies which demonstrate that this toxin is extremely useful for identifying biological processes that are controlled through the reversible phosphorylation of proteins. © 1990.

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页码：98 / 102

页数：5

相关论文

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