INTRATUBULARER DRUCK GLOMERULARER CAPILLARDRUCK UND GLOMERULUMFILTRAT WAHREND MANNIT-DIURESE

被引：50

作者：

KOCH, KM

DUME, T

KRAUSE, HH

OCHWADT, B

机构：

来源：

PFLUGERS ARCHIV FUR DIE GESAMTE PHYSIOLOGIE DES MENSCHEN UND DER TIERE | 1967年 / 295卷 / 01期

关键词：

D O I：

10.1007/BF00363905

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Glomerular filtration rate, proximal intratubular pressure during free-flow and proximal intratubular stop-flow pressure were measured in anesthetized rats before and during infusion of hypertonic solution of mannitol. The intratubular free-flow pressure increased with increased rates of urine flow whereas the glomerular filtration rate decreased in proportion to the increased intratubular pressure. The intratubular stop-flow pressure did not change during mannitol diuresis. The results are interpreted to mean that the decrease in glomerular filtration rate during osmotic diuresis is solely due to the increased intratubular pressure and that mannitol does not affect the glomerular capillary pressure.

引用

页码：72 / +

页数：1

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