LOW-DENSITY LIPOPROTEIN METABOLISM IN TYPE-IV AND TYPE-V HYPERLIPOPROTEINEMIA

被引：11

作者：

BROOK, JG

TORSVIK, H

LEES, RS

MCCLUSKEY, MA

FELDMAN, HA

机构：

[1] MIT,CTR ARTERIOSCLEROSIS,CAMBRIDGE,MA 02139

[2] MASSACHUSETTS GEN HOSP,CARDIAC UNIT,BOSTON,MA 02114

来源：

METABOLISM-CLINICAL AND EXPERIMENTAL | 1979年 / 28卷 / 01期

关键词：

D O I：

10.1016/0026-0495(79)90161-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Low density lipoproteins (LDL) are thought to arise largely from degradation of triglyceride-rich very-low-density lipoproteins (VLDL). LDL kinetics in patients with Type IV and Type V hyperlipoproteinmia were studied and compared with normal subjects. LDL labeled in the protein moiety with 125I was used as a tracer. There was no significant difference in LDL turnover between the three groups, suggesting that a catabolic defect in VLDL degradation to LDL may exist in both Type IV and Type V hyperlipoproteinemia. © 1979.

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页码：4 / 8

页数：5

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