THE EXPRESSION OF CYTOCHROME-P450IIB1 IN SACCHAROMYCES-CEREVISIAE RESULTS IN AN INCREASED MUTATION FREQUENCY WHEN EXPOSED TO CYCLOPHOSPHAMIDE

被引：25

作者：

BLACK, SM

ELLARD, S

MEEHAN, RR

PARRY, JM

ADESNIK, M

BEGGS, JD

WOLF, CR

机构：

[1] UNIV EDINBURGH,DEPT BIOCHEM,IMPERIAL CANC RES FUND,MOLEC PHARMACOL & DRUG METAB LAB,EDINBURGH EH8 9XD,SCOTLAND

[2] UNIV EDINBURGH,DEPT MOLEC BIOL,EDINBURGH EH9 3AN,SCOTLAND

[3] UNIV COLL SWANSEA,SCH BIOL SCI,SWANSEA SA2 8PP,W GLAM,WALES

[4] WESTERN GEN HOSP,MRC,CLIN & POPULAT CYTOGENET UNIT,EDINBURGH EH4 2XU,MIDLOTHIAN,SCOTLAND

[5] NYU MED CTR,DEPT CELL BIOL,NEW YORK,NY 10016

来源：

CARCINOGENESIS | 1989年 / 10卷 / 11期

关键词：

D O I：

10.1093/carcin/10.11.2139

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：2139 / 2143

页数：5

共 34 条

[1] IDENTIFICATION OF HUMAN CYTOCHROMES-P-450 ANALOGOUS TO FORMS INDUCED BY PHENOBARBITAL AND 3-METHYLCHOLANTHRENE IN THE RAT [J].

ADAMS, DJ ;

SEILMAN, S ;

AMELIZAD, Z ;

OESCH, F ;

WOLF, CR .

BIOCHEMICAL JOURNAL, 1985, 232 (03) :869-876

[2] HAIR DYES ARE MUTAGENIC - IDENTIFICATION OF A VARIETY OF MUTAGENIC INGREDIENTS [J].

AMES, BN ;

KAMMEN, HO ;

YAMASAKI, E .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1975, 72 (06) :2423-2427

[3]

AMMERER G, 1983, METHOD ENZYMOL, V101, P192

[4] 14-ALPHA-DEMETHYLATION OF LANOSTEROL BY A RECONSTITUTED CYTOCHROME-P-450 SYSTEM FROM YEAST MICROSOMES [J].

AOYAMA, Y ;

YOSHIDA, Y .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1978, 85 (01) :28-34

[5] NADPH-CYTOCHROME P-450 REDUCTASE OF YEAST MICROSOMES [J].

AOYAMA, Y ;

YOSHIDA, Y ;

KUBOTA, S ;

KUMAOKA, H ;

FURUMICHI, A .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1978, 185 (02) :362-369

[6] THE PROSPECTS FOR A SIMPLIFIED AND INTERNATIONALLY HARMONIZED APPROACH TO THE DETECTION OF POSSIBLE HUMAN CARCINOGENS AND MUTAGENS [J].

ASHBY, J .

MUTAGENESIS, 1986, 1 (01) :3-16

[7]

BIRNBOIM HC, 1979, NUCLEIC ACIDS RES, V7, P1513

[8]

Cox RA., 1968, METHODS ENZYMOL, V12, P120, DOI 10.1016/0076-6879(67)12123-X

[9] SYNTHESIS OF FUNCTIONAL-MOUSE CYTOCHROME-P-450-P1 AND CHIMERIC CYTOCHROME-P-450-P3-1 IN THE YEAST SACCHAROMYCES-CEREVISIAE [J].

CULLIN, C ;

POMPON, D .

GENE, 1988, 65 (02) :203-217

[10] INDUCTION OF SISTER CHROMATID EXCHANGES IN HUMAN AND RAT HEPATOMA-CELL LINES BY CYCLOPHOSPHAMIDE AND PHOSPHORAMIDE MUSTARD AND THE EFFECTS OF CYTOCHROME-P-450 INHIBITORS [J].

DEARFIELD, KL ;

JACOBSONKRAM, D ;

HUBER, BE ;

WILLIAMS, JR .

BIOCHEMICAL PHARMACOLOGY, 1986, 35 (13) :2199-2205

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