THE ASSOCIATION BETWEEN ALCOHOL AND BREAST-CANCER RISK - EVIDENCE FROM THE COMBINED ANALYSIS OF 6 DIETARY CASE-CONTROL STUDIES

被引：74

作者：

HOWE, G

ROHAN, T

DECARLI, A

ISCOVICH, J

KALDOR, J

KATSOUYANNI, K

MARUBINI, E

MILLER, A

RIBOLI, E

TONIOLO, P

TRICHOPOULOS, D

机构：

[1] UNIV MILAN, IST STAT MED & BIOMETRIA, I-20122 MILAN, ITALY

[2] MINIST HLTH, DEPT EPIDEMIOL STUDIES, LA PLATA, ARGENTINA

[3] ISRAEL CTR REGISTRAT CANC & ALLIED DIS, JERUSALEM, ISRAEL

[4] INT AGCY RES CANC, F-69372 LYONS, FRANCE

[5] UNIV ATHENS, DEPT HYG & EPIDEMIOL, ATHENS, GREECE

[6] UNIV TORONTO, FAC MED, DEPT PREVENT MED & BIOSTAT, TORONTO M5S 1A1, ONTARIO, CANADA

[7] NYU MED CTR, DEPT ENVIRONM MED, NEW YORK, NY 10016 USA

[8] HARVARD UNIV, SCH PUBL HLTH, BOSTON, MA 02115 USA

来源：

INTERNATIONAL JOURNAL OF CANCER | 1991年 / 47卷 / 05期

关键词：

D O I：

10.1002/ijc.2910470514

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Data from 1,575 cases and 1,974 controls enrolled in 6 previously conducted case-control studies of diet and breast cancer have been analysed with respect to alcohol intake. There appears to be an absence of any association between consumption of up to 40 g of alcohol per day and risk of breast cancer, and a highly statistically significant and consistent elevated risk of breast cancer for drinkers of 40 g or more of alcohol per day, for whom the relative risk, as compared with that of non-drinkers, is 1.69 (95% confidence interval 1.19 to 2.40). This association is not due to confounding by a number of diet-related factors, including total calories, fat, fibre and vitamin C.

引用

页码：707 / 710

页数：4

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