ALKALINE DEGRADATION OF DEOXYRIBONUCLEIC ACID DERIVATIVES

被引：44

作者：

JONES, AS

MIAN, AM

WALKER, RT

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC | 1968年 / 16期

关键词：

D O I：

10.1039/j39680002042

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Alkaline degradation of apurinic acid and apyrimidinic acid gave, in addition to oligonucleotides and inorganic phosphate, appreciable amounts of 2-oxocyclopent-1-enyl phosphate, identical with a sample obtained by the phosphorylation of cyclopentane-1,2-dione. A mechanism for the alkaline degradation of these deoxyribonucleic acid derivatives consistent with these results and those of other workers is proposed.

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页码：2042 / &

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