CHE1 UF SERUM-CHOLINESTERASE PHENOTYPE IN WHITES AND NON-WHITES FROM SOUTHERN BRAZIL AS DETERMINED BY A NEW METHOD

被引：6

作者：

ALCANTARA, VM ^{[1
]}

CHAUTARDFREIREMAIA, EA ^{[1
]}

CULPI, L ^{[1
]}

机构：

[1] UNIV FED PARANA,DEPT GENET,CAIXA POSTAL 19071,BR-81531 CURITIBA,PARANA,BRAZIL

来源：

HUMAN HEREDITY | 1991年 / 41卷 / 02期

关键词：

SERUM CHOLINESTERASE; FLUORIDE-RESISTANT ALLELE; POPULATION STUDY; SOUTH BRAZIL;

D O I：

10.1159/000153986

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A sample of 251 Whites and 818 Non-Whites, from Curitiba (southern Brazil), was typed with a new method with the aim of estimating the frequency of the CHE1*Fallele. The frequency of this allele did not differ between Whites (0.60 +/- 0.34%) and Non-Whites (0.49 +/- 0.17%), being estimated as 0.51 +/- 0.15% for the whole sample. The use of the inhibitors DL-propranolol and RO2-0683 with alpha-naphthylacetate as substrate (at 37-degrees-C) was efficient for discriminating between the CHE1 U and CHE1 UF phenotypes.

引用

页码：103 / 106

页数：4

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