MEDICATION EFFECTS - CONCEPTUAL AND METHODOLOGICAL ISSUES IN SCHIZOPHRENIA RESEARCH

被引：54

作者：

BLANCHARD, JJ ^{[1
]}

NEALE, JM ^{[1
]}

机构：

[1] SUNY STONY BROOK, STONY BROOK, NY 11794 USA

来源：

CLINICAL PSYCHOLOGY REVIEW | 1992年 / 12卷 / 03期

关键词：

D O I：

10.1016/0272-7358(92)90141-T

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

The majority of schizophrenia research is conducted with patients medicated with neuroleptics. This medication has powerful and widespread effects on various neurotransmitter systems. A review of the cognitive and motor side effects of neuroleptics, as well as the cognitive side effects of anticholinergic medication, leads to the conclusion that such side effects must be acknowledged as potentially serious confounds. Strategies available to researchers to assess, control for, or avoid these medication effects are discussed and their limitations noted. Finally, recent developments are discussed that may afford researchers an opportunity to more readily obtain drug-free patients; also, recommendations are provided for research conducted with medicated participants.

引用

页码：345 / 361

页数：17

共 72 条

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