STRAND-SPECIFIC FISH REVEALS ORIENTATION OF CHROMOSOME-18 ALPHOID DNA

被引：42

作者：

GOODWIN, E ^{[1
]}

MEYNE, J ^{[1
]}

机构：

[1] LOS ALAMOS NATL LAB,CTR HUMAN GENOME STUDIES,LOS ALAMOS,NM 87545

来源：

CYTOGENETICS AND CELL GENETICS | 1993年 / 63卷 / 02期

关键词：

D O I：

10.1159/000133516

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

A method is described for making in situ hybridization strand specific. Through the use of a synthetic DNA probe of a repetitive sequence in the centromeric region of chromosome 18, it is shown that the repeats exist in a head-to-tail tandem array. The method should be useful for studies of the molecular organization and mapping of chromosomes.

引用

页码：126 / &

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