D-ALPHA-AMINOADIPATE AS A SELECTIVE ANTAGONIST OF AMINO ACID-INDUCED AND SYNAPTIC EXCITATION OF MAMMALIAN SPINAL NEURONS

被引：117

作者：

BISCOE, TJ

EVANS, RH

FRANCIS, AA

MARTIN, MR

WATKINS, JC

机构：

[1] UNIV BRISTOL,SCH MED,DEPT PHYSIOL,BRISTOL BS8 1TH,AVON,ENGLAND

[2] UNIV BRISTOL,SCH MED,DEPT PHARMACOL,BRISTOL BS8 1TH,AVON,ENGLAND

[3] UNIV LONDON,SCH PHARM,DEPT PHARMACOL,LONDON WC1,ENGLAND

来源：

NATURE | 1977年 / 270卷 / 5639期

关键词：

D O I：

10.1038/270743a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：743 / 745

页数：3

共 9 条

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JOURNAL OF THE NEUROLOGICAL SCIENCES, 1977, 31 (01) :51-61

[2] DEPRESSION OF SYNAPTIC EXCITATION AND OF AMINO-ACID INDUCED EXCITATORY RESPONSES OF SPINAL NEURONS BY D-ALPHA-AMINOADIPATE, ALPHA,EPSILON-DIAMINOPIMELIC ACID AND HA-966 [J].

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[3]

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[4] CHANGES IN AMINO ACID CONCENTRATIONS ASSOCIATED WITH LOSS OF SPINAL INTERNEURONS [J].

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APRISON, MH .

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[5] EFFECT OF MAGNESIUM-IONS ON RESPONSES OF SPINAL NEURONS TO EXCITATORY AMINO-ACIDS AND ACETYLCHOLINE [J].

DAVIES, J ;

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BRAIN RESEARCH, 1977, 130 (02) :364-368

[6]

DUGGAN AW, 1974, EXP BRAIN RES, V19, P522

[7]

HALL JG, 1977, J PHYSIOL-LONDON, V272, pP52

[8] SPINAL INTERNEURON EXCITATION BY CONFORMATIONALLY RESTRICTED ANALOGS OF L-GLUTAMIC ACID [J].

JOHNSTON, GA ;

CURTIS, DR ;

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MCCULLOCH, RM .

NATURE, 1974, 248 (5451) :804-805

[9]

MCCULLOCH RM, 1974, EXP BRAIN RES, V21, P515

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