SAFETY ASPECTS OF TRANSCRANIAL BRAIN-STIMULATION IN MAN TESTED BY SINGLE PHOTON EMISSION-COMPUTED TOMOGRAPHY

被引：31

作者：

DRESSLER, D

VOTH, E

FELDMANN, M

BENECKE, R

机构：

[1] UNIV GOTTINGEN,DEPT CLIN NEUROPHYSIOL,W-3400 GOTTINGEN,GERMANY

[2] UNIV GOTTINGEN,DEPT NUCL MED,W-3400 GOTTINGEN,GERMANY

[3] UNIV GOTTINGEN,DEPT NEUROL,W-3400 GOTTINGEN,GERMANY

来源：

NEUROSCIENCE LETTERS | 1990年 / 119卷 / 02期

关键词：

!sup]99m[!/sup]Tc-HMPAO SPECT; Electric brain stimulation; Magnetic brain stimulation; Regional cerebral blood flow; Safety aspect;

D O I：

10.1016/0304-3940(90)90821-P

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Single photon emission-computed tomography (SPECT) using 99mTc-labelled hexamethylpropyleneamine oxime (99mTc-HMPAO), a new method to visualize regional cerebral blood flow (rCBF) and epileptogenic foci, was used to study acute and long-term effects of transcranial brain stimulation. Magnetic and electric brain stimulation increase rCBF not more than voluntary muscle activation mimicking the motor effects of transcranial brain stimulation. Focal rCBF increase, typical for epileptogenic foci, or other pathological findings could not be detected even when the subject had received several thousand stimulations in the past. Transcranial brain stimulation does not produce rCBF patterns indicating acute or chronic adverse effects. © 1990.

引用

页码：153 / 155

页数：3

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