ROLE OF MATERNAL ANTIBODY IN PNEUMONIA AND BRONCHIOLITIS DUE TO RESPIRATORY SYNCYTIAL VIRUS

被引：148

作者：

LAMPRECHT, CL

KRAUSE, HE

MUFSON, MA

机构：

[1] UNIV ILLINOIS, ABRAHAM LINCOLN SCH MED, DEPT MED, CHICAGO, IL 60680 USA

[2] UNIV ILLINOIS, ABRAHAM LINCOLN SCH MED, DEPT PREVENT MED & COMMUNITY HLTH, CHICAGO, IL 60680 USA

[3] W SIDE VET ADM HOSP, CHICAGO, IL USA

来源：

JOURNAL OF INFECTIOUS DISEASES | 1976年 / 134卷 / 03期

关键词：

D O I：

10.1093/infdis/134.3.211

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Fifteen infants with pneumonia caused by respiratory syncytial virus (RSV) and 19 infants with bronchiolitis caused by RSV were studied for the influence of homologous, circulating neutralizing antibody on the severity of their illness. All infants were under 9 mo. old. Although maternal neutralizing antibody did not prevent infection with RSV and illness, the severity of pneumonia caused by RSV was inversely related to the level of neutralizing antibody. The severity of bronchiolitis caused by RSV was unrelated to maternal antibody levels. Chest roentgenograms showed pneumonia to be slightly more severe than bronchiolitis. Neither the severity of illness nor the presence of maternal neutralizing antibody was related to the development of complement-fixing antibody.

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页码：211 / 217

页数：7

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