TRANSFORMATION OF HUMAN LYMPHOCYTES - INHIBITION BY HOMOLOGOUS ALPHA GLOBULIN

被引：256

作者：

COOPERBAND, SR

BONDEVIK, H

SCHMID, K

MANNICK, JA

机构：

[1] Departments of Medicine, Microbiology, Biochemistry, and Surgery, Boston University School of Medicine, Boston

来源：

SCIENCE | 1968年 / 159卷 / 3820期

关键词：

D O I：

10.1126/science.159.3820.1243

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

An alpha globulin fraction prepared from normal human plasma by column chromatography prevents homologous lymphocyte transformation and the stimulation of DNA, and also protein synthesis induced by phytohemagglutinin and specific antigens. These observations support the concept of a normal circulating immunosuppressant factor which prevents lymphoid cell proliferation.

引用

页码：1243 / +

页数：1

共 17 条

[1] ROLE OF THYMUS AND OTHER CENTRAL LYMPHOID TISSUES IN IMMUNOLOGICAL DISEASE [J].

COOPER, MD ;

GABRIELSEN, AE ;

GOOD, RA .

ANNUAL REVIEW OF MEDICINE, 1967, 18 :113-+

[2]

COOPERBAND SR, IN PRESS

[3]

COPPERBA.SR, 1967, NATURE, V214, P1240

[4] EFFECT OF PASSIVELY ADMINISTERED ANTIBODY ON ANTIBODY SYNTHESIS [J].

DIXON, FJ ;

JACOTGUI.H ;

MCCONAHEY, PJ .

JOURNAL OF EXPERIMENTAL MEDICINE, 1967, 125 (06) :1119-+

[5] PREPARATION AND PROPERTIES OF THYMOSTATIN A NEW THYMIC INHIBITOR OF DNA AND RNA SYNTHESIS [J].

GOLDSTEI.AL ;

BANERJEE, S ;

WHITE, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1967, 57 (03) :821-&

[6]

KAMRIN BB, 1959, P SOC EXP BIOL MED, V100, P58

[7] EFFECT OF SABIN TYPE 1 POLIOMYELITIS VACCINE ADMINISTERED BY MOUTH TO NEWBORN INFANTS [J].

LEPOW, ML ;

INGRAM, VG ;

WARREN, RJ ;

GRAY, N ;

ROBBINS, FC .

NEW ENGLAND JOURNAL OF MEDICINE, 1961, 264 (21) :1071-+

[8]

MANNICK JA, 1967, TRANSPLANTATION, V5, P1231

[9]

MERCHANT DJ, 1960, HANDBOOK CELL ORGAN

[10] EFFECT OF LARGE DOSES OF AN ALPHA-2-GLYCOPROTEIN FRACTION ON THE SURVIVAL OF RAT SKIN HOMOGRAFTS [J].

MOWBRAY, JF .

TRANSPLANTATION, 1963, 1 (01) :15-20

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