BIOSYNTHESIS OF ML-236B (COMPACTIN) AND MONACOLIN-K

被引：40

作者：

ENDO, A

NEGISHI, Y

IWASHITA, T

MIZUKAWA, K

HIRAMA, M

机构：

[1] SUNTORY INST BIOORGAN RES,SHIMAMOTO,OSAKA 618,JAPAN

[2] TOHOKU UNIV,DEPT CHEM,SENDAI,MIYAGI 980,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1985年 / 38卷 / 03期

关键词：

D O I：

10.7164/antibiotics.38.444

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：444 / 448

页数：5

共 21 条

[1] MEVINOLIN - A HIGHLY POTENT COMPETITIVE INHIBITOR OF HYDROXYMETHYLGLUTARYL-COENZYME-A REDUCTASE AND A CHOLESTEROL-LOWERING AGENT [J].

ALBERTS, AW ;

CHEN, J ;

KURON, G ;

HUNT, V ;

HUFF, J ;

HOFFMAN, C ;

ROTHROCK, J ;

LOPEZ, M ;

JOSHUA, H ;

HARRIS, E ;

PATCHETT, A ;

MONAGHAN, R ;

CURRIE, S ;

STAPLEY, E ;

ALBERSSCHONBERG, G ;

HENSENS, O ;

HIRSHFIELD, J ;

HOOGSTEEN, K ;

LIESCH, J ;

SPRINGER, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (07) :3957-3961

[2]

BAX A, 1982, 2 DIMENSIONAL NUCLEA, P51

[3] CRYSTAL AND MOLECULAR-STRUCTURE OF COMPACTIN, A NEW ANTIFUNGAL METABOLITE FROM PENICILLIUM-BREVICOMPACTUM [J].

BROWN, AG ;

SMALE, TC ;

KING, TJ ;

HASENKAMP, R ;

THOMPSON, RH .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1976, (11) :1165-1173

[4] BIOSYNTHESIS OF MEVINOLIN - SPECTRAL ASSIGNMENT BY DOUBLE-QUANTUM COHERENCE NMR AFTER HIGH C-13 INCORPORATION [J].

CHAN, JK ;

MOORE, RN ;

NAKASHIMA, TT ;

VEDERAS, JC .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1983, 105 (10) :3334-3336

[5] BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY OF INHIBITORS OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME-A REDUCTASE [J].

ENDO, A .

TRENDS IN BIOCHEMICAL SCIENCES, 1981, 6 (01) :10-13

[6] MONACOLIN-K, A NEW HYPOCHOLESTEROLEMIC AGENT PRODUCED BY A MONASCUS SPECIES [J].

ENDO, A .

JOURNAL OF ANTIBIOTICS, 1979, 32 (08) :852-854

[7] ML-236A, ML-236B, AND ML-236C, NEW INHIBITORS OF CHOLESTEROGENESIS PRODUCED BY PENICILLIUM CITRINUM [J].

ENDO, A ;

KURODA, M ;

TSUJITA, Y .

JOURNAL OF ANTIBIOTICS, 1976, 29 (12) :1346-1348

[8]

ENDO A, 1985, J ANTIBIOTICS, V38, P333

[9]

ENDO A, 1985, J MED CHEM, V28

[10]

ENDO A, 1983, ANN M AGR CHEM SOC J, P134

← 1 2 3 →