BRODIOSIDE B, A NOVEL (20R,22S)-SPIROSTANOL TETRASACCHARIDE FROM BRODIAEA-CALIFORNICA TUBERS

被引：4

作者：

NAKAMURA, O

MIMAKI, Y

SASHIDA, Y

NIKAIDO, T

OHMOTO, T

机构：

[1] TOKYO COLL PHARM, HACHIOJI, TOKYO 19203, JAPAN

[2] TOHO UNIV, FAC PHARMACEUT SCI, FUNABASHI, CHIBA 274, JAPAN

来源：

CHEMISTRY LETTERS | 1994年 / 04期

关键词：

D O I：

10.1246/cl.1994.805

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel (20R,22S)-spirostanol tetrasaccharide, named brodioside B, was isolated from Brodiaea californica together with a new (25S)-ruscogenin tetrasaccharide, named brodioside A. Their structures were determined by extensive 2D NMR analysis and hydrolysis. Brodiosides A and B were active as a cyclic AMP phosphodiesterase inhibitor.

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页码：805 / 808

页数：4

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