NMDA-DEPENDENT INDUCTION OF LONG-TERM POTENTIATION IN AFFERENT AND ASSOCIATION FIBER SYSTEMS OF PIRIFORM CORTEX INVITRO

被引：138

作者：

KANTER, ED

HABERLY, LB

机构：

[1] UNIV WISCONSIN,DEPT ANAT,1300 UNIV AVE,MADISON,WI 53706

[2] UNIV WISCONSIN,NEUROSCI TRAINING PROGRAM,MADISON,WI 53706

来源：

BRAIN RESEARCH | 1990年 / 525卷 / 01期

关键词：

Long-term potentiation; N-methyl-d-aspartate; Olfaction; Piriform cortex; Synaptic plasticity;

D O I：

10.1016/0006-8993(90)91337-G

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Long-term potentiation (LTP) was demonstrated in a slice preparation of piriform (olfactory) cortex. LTP could be reliably induced in both afferent and association fiber pathways. The magnitude of the observed potentiation was greater in the association fiber pathway. 2-Amino-5-phosphonovalerate (APV) blocked induction of LTP in both pathways, indicating that N-methyl-d-aspartate (NMDA) receptor activation is required for induction. © 1990.

引用

页码：175 / 179

页数：5

共 20 条

[1] POSTSYNAPTIC CONTROL OF THE INDUCTION OF LONG-TERM CHANGES IN EFFICACY OF TRANSMISSION AT NEOCORTICAL SYNAPSES IN SLICES OF RAT-BRAIN [J].