THE RAS SIGNALING PATHWAY IN DROSOPHILA

被引：197

作者：

WASSARMAN, DA

THERRIEN, M

RUBIN, GM

机构：

[1] DA Wassarman, M Therrien and GM Rubin, Department of Molecular and Cell Biology, Howard Hughes Medical Institute, University of California at Berkeley, Berkeley

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1995年 / 5卷 / 01期

关键词：

D O I：

10.1016/S0959-437X(95)90052-7

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

During Drosophila eye development, a Ras cascade mediates the decision between neuronal and non-neuronal differentiation of the R7 photoreceptor precursor. Recent genetic and molecular studies have identified a set of protein kinases as components of the Ras cascade and nuclear targets of the cascade, including Yan, Pointed, Jun, and Phyllopod. The Ras cascade functions in other Drosophila signal transduction pathways, eliciting a distinct response in each case, presumably through phosphorylation of specific transcription factors.

引用

页码：44 / 50

页数：7

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