QUANTITATIVE ASPECTS OF HORMONE-RECEPTOR INTERACTIONS OF HIGH AFFINITY - EFFECT OF RECEPTOR CONCENTRATION AND MEASUREMENT OF DISSOCIATION-CONSTANTS OF LABELED AND UNLABELED HORMONES

被引：228

作者：

CHANG, KJ

JACOBS, S

CUATRECASAS, P

机构：

[1] JOHNS HOPKINS UNIV,SCH MED,DEPT PHARMACOL & EXPTL THERAPEUT,BALTIMORE,MD 21205

[2] JOHNS HOPKINS UNIV,SCH MED,DEPT MED,BALTIMORE,MD 21205

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1975年 / 406卷 / 02期

关键词：

D O I：

10.1016/0005-2736(75)90011-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：294 / 303

页数：10

共 17 条

[1] ACTIVATION OF PROTEIN KINASE BY PHYSIOLOGICAL CONCENTRATIONS OF CYCLIC-AMP [J].

BEAVO, JA ;

BECHTEL, PJ ;

KREBS, EG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1974, 71 (09) :3580-3583

[2]

CHA S, 1970, J BIOL CHEM, V245, P4814

[3] MEMBRANE RECEPTORS [J].

CUATRECASAS, P .

ANNUAL REVIEW OF BIOCHEMISTRY, 1974, 43 :169-214

[4] BINDING OF INSULIN AND OTHER HORMONES TO NON-RECEPTOR MATERIALS - SATURABILITY, SPECIFICITY AND APPARENT NEGATIVE-COOPERATIVITY [J].

CUATRECASAS, P ;

HOLLENBERG, MD .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1975, 62 (01) :31-41

[5]

CUATRECASAS P, 1975, RECENT PROGR HORMONE, V31

[6] The mechanism of enzyme-inhibitor-substrate reactions [J].

Goldstein, A .

JOURNAL OF GENERAL PHYSIOLOGY, 1944, 27 (06) :529-580

[7]

GRUNLAKSHANA O, 1939, BRIT J PHARMACOL, V14, P48

[8]

JACOBS SA, TO BE PUBLISHED

[9] PROPERTIES OF GRAPHICAL REPRESENTATIONS OF MULTIPLE CLASSES OF BINDING SITES [J].

KLOTZ, IM ;

HUNSTON, DL .

BIOCHEMISTRY, 1971, 10 (16) :3065-&

[10] COMPARISON OF EXPERIMENTAL BINDING DATA AND THEORETICAL MODELS IN PROTEINS CONTAINING SUBUNITS [J].

KOSHLAND, DE ;

NEMETHY, G ;

FILMER, D .

BIOCHEMISTRY, 1966, 5 (01) :365-+

← 1 2 →