A NEW CYTOKINE RECEPTOR SUPERFAMILY

被引：497

作者：

COSMAN, D

LYMAN, SD

IDZERDA, RL

BECKMANN, MP

PARK, LS

GOODWIN, RG

MARCH, CJ

机构：

[1] Immunex Corporation, Seattle, WA 98101

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1990年 / 15卷 / 07期

关键词：

D O I：

10.1016/0968-0004(90)90051-C

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The amino acid sequences of several, recently cloned cytokine receptors show significant homologies, primarily in their extracellular, ligand-binding domains. With one exception, their cognate cytokines mediate biological activities on a variety of hemotopoietic cell types; thus we have designated the receptors as the hematopoietin receptor superfamily. © 1990.

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收藏

页码：265 / 270

页数：6

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