ACTIVE-SITE MUTANTS OF BETA-LACTAMASE - USE OF AN INACTIVE DOUBLE MUTANT TO STUDY REQUIREMENTS FOR CATALYSIS

被引：56

作者：

DALBADIEMCFARLAND, G ^{[1
]}

NEITZEL, JJ ^{[1
]}

RICHARDS, JH ^{[1
]}

机构：

[1] CALTECH,DIV CHEM & CHEM ENGN,PASADENA,CA 91125

来源：

BIOCHEMISTRY | 1986年 / 25卷 / 02期

关键词：

D O I：

10.1021/bi00350a008

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：332 / 338

页数：7

共 38 条

[1] THE STRUCTURE OF BETA-LACTAMASES [J].

AMBLER, RP .

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 1980, 289 (1036) :321-331

[2] PARTIAL AMINO-ACID SEQUENCE OF PENICILLINASE CODED BY ESCHERICHIA-COLI PLASMID R6K [J].

AMBLER, RP ;

SCOTT, GK .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1978, 75 (08) :3732-3736

[3]

BASSFORD PJ, 1979, J BACTERIOL, V139, P19, DOI 10.1128/JB.139.1.19-31.1979

[4] MISMATCH REPAIR IN STREPTOCOCCUS-PNEUMONIAE - RELATIONSHIP BETWEEN BASE MISMATCHES AND TRANSFORMATION EFFICIENCIES [J].

CLAVERYS, JP ;

MEJEAN, V ;

GASC, AM ;

SICARD, AM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (19) :5956-5960

[5] REDESIGNING TRYPSIN - ALTERATION OF SUBSTRATE-SPECIFICITY [J].

CRAIK, CS ;

LARGMAN, C ;

FLETCHER, T ;

ROCZNIAK, S ;

BARR, PJ ;

FLETTERICK, R ;

RUTTER, WJ .

SCIENCE, 1985, 228 (4697) :291-297

[6]

DALBADIEMCFARLA.G, 1985, THESIS CALTECH

[7] OLIGONUCLEOTIDE-DIRECTED MUTAGENESIS AS A GENERAL AND POWERFUL METHOD FOR STUDIES OF PROTEIN FUNCTION [J].

DALBADIEMCFARLAND, G ;

COHEN, LW ;

RIGGS, AD ;

MORIN, C ;

ITAKURA, K ;

RICHARDS, JH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (21) :6409-6413

[8] PENICILLINASE SYNTHESIS CONTROLLED BY INFECTIOUS R FACTORS IN ENTEROBACTERIACEAE [J].

DATTA, N ;

KONTOMICHALOU, P .

NATURE, 1965, 208 (5007) :239-+

[9]

DEBOER HA, 1983, P NATL ACAD SCI-BIOL, V80, P21

[10] REPAIR OF DEFINED SINGLE BASE-PAIR MISMATCHES IN ESCHERICHIA-COLI [J].

DOHET, C ;

WAGNER, R ;

RADMAN, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (02) :503-505

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