REGIONAL BRAIN VARIATIONS OF TRYPTOPHAN, MONOAMINES, MONOAMINE-OXIDASE ACTIVITY, PLASMA-FREE AND TOTAL TRYPTOPHAN DURING ESTROUS-CYCLE OF RAT

被引：42

作者：

KUENG, W ^{[1
]}

WIRZJUSTICE, A ^{[1
]}

MENZI, R ^{[1
]}

CHAPPUISARNDT, E ^{[1
]}

机构：

[1] UNIV BASLE, PSYCHIAT CLIN, BIOCHEM LAB, CH-4025 BASLE, SWITZERLAND

来源：

NEUROENDOCRINOLOGY | 1976年 / 21卷 / 04期

关键词：

D O I：

10.1159/000122536

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Normal 4 day cyclic rats were sacrificed at 10 a.m. and 3 p.m. on proestrus or estrus and at 10 a.m. on metestrus. Noradrenaline (NA) [norepinephrine] dopamine (DA) and tryptophan (T) concentrations varied only slightly. Serotonin (5-HT) concentrations showed characteristics changing patterns in many hypothalamic, limbic and midbrain structures with a decrease during proestrus and an increase during estrus being observed. Monoamine oxidase (MAO) activity changes were often parallel to the 5-HT changes, but were not as great. The marked changes in 5-HT early in proestrus are a further indication of its inhibitory effect on gonadotropin release mechanisms before the critical period.

引用

页码：289 / 296

页数：8

共 28 条

[1] TURNOVER CHANGES IN TUBERO-INFUNDIBULAR DOPAMINE NEURONS DURING OVARIAN CYCLE OF RAT [J].

AHREN, K ;

FUXE, K ;

HAMBERGER, L ;

HOKFELT, T .

ENDOCRINOLOGY, 1971, 88 (06) :1415-+

[2]

BLOOM FE, 1973, SEROTONIN BEHAVIOR, P249

[3] PLASMA CONCENTRATION OF LH, FSH, PROLACTIN, PROGESTERONE AND ESTRADIOL-17BETA THROUGHOUT 4-DAY ESTROUS-CYCLE OF RAT [J].

BUTCHER, RL ;

COLLINS, WE ;

FUGO, NW .

ENDOCRINOLOGY, 1974, 94 (06) :1704-1708

[4]

DENCKLA WD, 1967, J LAB CLIN MED, V69, P160

[5] DRUG EFFECTS AND HYPOTHALAMIC-ANTERIOR PITUITARY-FUNCTION [J].

DEWIED, D ;

DEJONG, W .

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 1974, 14 :389-412

[6]

Fuxe K, 1974, Adv Biochem Psychopharmacol, V10, P1

[7] MONOAMINE OXIDASE ACTIVITY IN HYPOTHALAMUS AND VARIOUS OTHER BRAIN AREAS AND IN SOME ENDOCRINE GLANDS OF RAT DURING ESTRUS CYCLE [J].

KAMBERI, IA ;

KOBAYASHI, Y .

JOURNAL OF NEUROCHEMISTRY, 1970, 17 (02) :261-+

[8]

KAPELLERADLER R, 1970, AMINE OXIDASES METHO, P178

[9] CHANGES IN MULTIPLE UNIT ACTIVITY OF BRAIN DURING ESTROUS CYCLE [J].

KAWAKAMI, M ;

TERASAWA, E ;

IBUKI, T .

NEUROENDOCRINOLOGY, 1970, 6 (01) :30-&

[10]

KOENIG JFR, 1963, RAT BRAIN STEREOTAXI

← 1 2 3 →