TRANSMISSION AND AGE-AT-ONSET PATTERNS IN FAMILIAL ALZHEIMERS-DISEASE - EVIDENCE FOR HETEROGENEITY

被引：112

作者：

FARRER, LA

MYERS, RH

CUPPLES, LA

GEORGEHYSLOP, PHS

BIRD, TD

ROSSOR, MN

MULLAN, MJ

POLINSKY, R

NEE, L

HESTON, L

VAN BROECKHOVEN, C

MARTIN, JJ

CRAPPERMCLACHLAN, D

GROWDON, JH

机构：

[1] BOSTON UNIV, SCH MED, SCH PUBL HLTH, BOSTON, MA 02118 USA

[2] HARVARD UNIV, SCH MED, DEPT NEUROL, BOSTON, MA 02115 USA

[3] HARVARD UNIV, SCH MED, NEUROGENET LAB, BOSTON, MA 02115 USA

[4] UNIV WASHINGTON, SCH MED, DEPT NEUROL, SEATTLE, WA 98195 USA

[5] VET ADM MED CTR, SEATTLE, WA 98108 USA

[6] ST MARYS HOSP, SCH MED, DEPT NEUROL, LONDON, ENGLAND

[7] ST MARYS HOSP, SCH MED, DEPT BIOCHEM, LONDON, ENGLAND

[8] ST MARYS HOSP, SCH MED, DEPT MOLEC BIOL, LONDON, ENGLAND

[9] NINCDS, BETHESDA, MD 20205 USA

[10] UNIV MINNESOTA, DEPT PSYCHIAT, MINNEAPOLIS, MN 55455 USA

[11] UNIV INSTELLING ANTWERP, DEPT BIOCHEM, B-2610 WILRIJK, BELGIUM

[12] UNIV INSTELLING ANTWERP, DEPT NEUROL, B-2610 WILRIJK, BELGIUM

[13] UNIV TORONTO, DEPT NEUROL, TORONTO M5S 1A1, ONTARIO, CANADA

来源：

NEUROLOGY | 1990年 / 40卷 / 03期

关键词：

D O I：

10.1212/WNL.40.3_Part_1.395

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

引用

页码：395 / 403

页数：9

共 74 条

[1] A POPULATION STUDY OF SENILE AND ARTERIOSCLEROTIC PSYCHOSES [J].

AKESSON, HO .

HUMAN HEREDITY, 1969, 19 (05) :546-&

[2] GENETIC-LINKAGE BETWEEN X-CHROMOSOME MARKERS AND BIPOLAR AFFECTIVE-ILLNESS [J].

BARON, M ;

RISCH, N ;

HAMBURGER, R ;

MANDEL, B ;

KUSHNER, S ;

NEWMAN, M ;

DRUMER, D ;

BELMAKER, RH .

NATURE, 1987, 326 (6110) :289-292

[3] PHENOTYPIC HETEROGENEITY IN FAMILIAL ALZHEIMERS-DISEASE - A STUDY OF 24 KINDREDS [J].

BIRD, TD ;

SUMI, SM ;

NEMENS, EJ ;

NOCHLIN, D ;

SCHELLENBERG, G ;

LAMPE, TH ;

SADOVNICK, A ;

CHUI, H ;

MINER, GW ;

TINKLENBERG, J .

ANNALS OF NEUROLOGY, 1989, 25 (01) :12-25

[4] FAMILIAL ALZHEIMERS-DISEASE IN AMERICAN DESCENDANTS OF THE VOLGA GERMANS - PROBABLE GENETIC FOUNDER EFFECT [J].

BIRD, TD ;

LAMPE, TH ;

NEMENS, EJ ;

MINER, GW ;

SUMI, SM ;

SCHELLENBERG, GD .

ANNALS OF NEUROLOGY, 1988, 23 (01) :25-31

[5]

BRAYNE C, 1988, LANCET, V1, P1265

[6] AGE-DEPENDENT EXPRESSION OF FAMILIAL RISK IN ALZHEIMERS-DISEASE [J].

BREITNER, JCS ;

MURPHY, EA ;

SILVERMAN, JM ;

MOHS, RC ;

DAVIS, KL .

AMERICAN JOURNAL OF EPIDEMIOLOGY, 1988, 128 (03) :536-548

[7]

BREITNER JCS, 1988, NEUROLOGY, V38, P207

[8] FAMILIAL AGGREGATION IN ALZHEIMER DEMENTIA .1. A MODEL FOR THE AGE-DEPENDENT EXPRESSION OF AN AUTOSOMAL DOMINANT GENE [J].

BREITNER, JCS ;

FOLSTEIN, MF ;

MURPHY, EA .

JOURNAL OF PSYCHIATRIC RESEARCH, 1986, 20 (01) :31-43

[9] THE USE OF LIFE-TABLES AND SURVIVAL ANALYSIS IN TESTING GENETIC HYPOTHESES, WITH AN APPLICATION TO ALZHEIMERS-DISEASE [J].

CHASE, GA ;

FOLSTEIN, MF ;

BREITNER, JCS ;

BEATY, TH ;

SELF, SG .

AMERICAN JOURNAL OF EPIDEMIOLOGY, 1983, 117 (05) :590-597

[10] CLINICAL SUBTYPES OF DEMENTIA OF THE ALZHEIMER TYPE [J].

CHUI, HC ;

TENG, EL ;

HENDERSON, VW ;

MOY, AC .

NEUROLOGY, 1985, 35 (11) :1544-1550

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