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CELLULAR UPTAKE OF MISONIDAZOLE AND ANALOGS WITH ACIDIC OR BASIC FUNCTIONS

被引：95
作者：
DENNIS, MF
STRATFORD, MRL
WARDMAN, P
WATTS, ME
机构：
来源：
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY | 1985年 / 47卷 / 06期
关键词：
D O I：
10.1080/09553008514550871
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
收藏
页码：629 / 643
页数：15
相关论文
共 38 条
[1]   STRUCTURE-ACTIVITY-RELATIONSHIPS IN THE DEVELOPMENT OF HYPOXIC CELL RADIOSENSITIZERS .3. EFFECTS OF BASIC SUBSTITUENTS IN NITROIMIDAZOLE SIDECHAINS [J].
ADAMS, GE ;
AHMED, I ;
CLARKE, ED ;
ONEILL, P ;
PARRICK, J ;
STRATFORD, IJ ;
WALLACE, RG ;
WARDMAN, P ;
WATTS, ME .
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, 1980, 38 (06) :613-626
[2]   STRUCTURE-ACTIVITY-RELATIONSHIPS IN THE DEVELOPMENT OF HYPOXIC CELL RADIOSENSITIZERS .1. SENSITIZATION EFFICIENCY [J].
ADAMS, GE ;
CLARKE, ED ;
FLOCKHART, IR ;
JACOBS, RS ;
SEHMI, DS ;
STRATFORD, IJ ;
WARDMAN, P ;
WATTS, ME ;
PARRICK, J ;
WALLACE, RG ;
SMITHEN, CE .
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, 1979, 35 (02) :133-150
[3]   STRUCTURE-ACTIVITY-RELATIONSHIPS IN THE DEVELOPMENT OF HYPOXIC CELL RADIOSENSITIZERS .2. CYTOTOXICITY AND THERAPEUTIC RATIO [J].
ADAMS, GE ;
CLARKE, ED ;
GRAY, P ;
JACOBS, RS ;
STRATFORD, IJ ;
WARDMAN, P ;
WATTS, ME ;
PARRICK, J ;
WALLACE, RG ;
SMITHEN, CE .
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, 1979, 35 (02) :151-160
[4]   ELECTRON-AFFINIC SENSITIZATION .7. CORRELATION BETWEEN STRUCTURES ONE-ELECTRON REDUCTION POTENTIALS, AND EFFICIENCIES OF NITROIMIDAZOLES AS HYPOXIC CELL RADIOSENSITIZERS [J].
ADAMS, GE ;
FLOCKHART, IR ;
SMITHEN, CE ;
STRATFORD, IJ ;
WARDMAN, P ;
WATTS, ME .
RADIATION RESEARCH, 1976, 67 (01) :9-20
[5]   COMPARISON OF MICROELECTRODE, DMO, AND METHYLAMINE METHODS FOR MEASURING INTRACELLULAR PH [J].
BORON, WF ;
ROOS, A .
AMERICAN JOURNAL OF PHYSIOLOGY, 1976, 231 (03) :799-809
[6]   FACTORS INFLUENCING INTRACELLULAR UPTAKE AND RADIOSENSITIZATION BY 2-NITROIMIDAZOLES INVITRO [J].
BROWN, DM ;
GONZALEZMENDEZ, R ;
BROWN, JM .
RADIATION RESEARCH, 1983, 93 (03) :492-505
[7]   PARTITION-COEFFICIENT AS A GUIDE TO THE DEVELOPMENT OF RADIOSENSITIZERS WHICH ARE LESS TOXIC THAN MISONIDAZOLE [J].
BROWN, JM ;
WORKMAN, P .
RADIATION RESEARCH, 1980, 82 (01) :171-190
[8]   CLINICAL-TRIALS OF RADIOSENSITIZERS - WHAT SHOULD WE EXPECT [J].
BROWN, JM .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1984, 10 (03) :425-429
[9]  
CALDERWOOD SK, 1983, ADV RADIAT BIOL, V10, P135
[10]   MISONIDAZOLE - DRUG FOR TRIAL IN RADIOTHERAPY AND ONCOLOGY [J].
DISCHE, S ;
SAUNDERS, MI ;
FLOCKHART, IR ;
LEE, ME ;
ANDERSON, P .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1979, 5 (06) :851-860
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