GENETIC-MAPPING OF QUANTITATIVE TRAIT LOCI FOR GROWTH AND FATNESS IN PIGS

被引：541

作者：

ANDERSSON, L

HALEY, CS

ELLEGREN, H

KNOTT, SA

JOHANSSON, M

ANDERSSON, K

ANDERSSONEKLUND, L

EDFORSLILJA, I

FREDHOLM, M

HANSSON, I

HAKANSSON, J

LUNDSTROM, K

机构：

[1] AFRC,ROSLIN INST EDINBURGH,ROSLIN EH25 9PS,MIDLOTHIAN,SCOTLAND

[2] INRA,GENET QUANTITAT & APPL STN,F-78350 JOUY EN JOSAS,FRANCE

[3] UNIV EDINBURGH,INST CELL ANIM & POPULAT BIOL,EDINBURGH EH9 3JT,SCOTLAND

[4] ROYAL VET & AGR UNIV,DEPT ANIM PROD & ANIM HLTH,DIV ANIM GENET,DK-1870 FREDERIKSBERG C,DENMARK

[5] SWEDISH UNIV AGR SCI,DEPT FOOD SCI,S-75007 UPPSALA,SWEDEN

[6] SWEDISH UNIV AGR SCI,DEPT ANIM NUTR & MANAGEMENT,S-75007 UPPSALA,SWEDEN

来源：

SCIENCE | 1994年 / 263卷 / 5154期

关键词：

D O I：

10.1126/science.8134840

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The European wild boar was crossed with the domesticated Large White pig to genetically dissect phenotypic differences between these populations for growth and fat deposition. The most important effects were clustered on chromosome 4, with a single region accounting for a large part of the breed difference in growth rate, fatness, and length of the small intestine. The study is an advance in genome analyses and documents the usefulness of crosses between divergent outbred populations for the detection and characterization of quantitative trait loci. The genetic mapping of a major locus for fat deposition in the pig could have implications for understanding human obesity.

引用

页码：1771 / 1774

页数：4

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