NEW APPROACHES TO AMPHIBIAN LIMB REGENERATION

被引：27

作者：

BROCKES, JP ^{[1
]}

机构：

[1] UCL, DEPT BIOCHEM & MOLEC BIOL, LONDON W1P 8BT, ENGLAND

来源：

TRENDS IN GENETICS | 1994年 / 10卷 / 05期

关键词：

D O I：

10.1016/0168-9525(94)90094-9

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Limb regeneration in urodele amphibians proceeds by the formation of a blastema, a growth zone of mesenchymal progenitor cells. Here, I review the origin of the blastema and its positional identity. The ability to culture and reimplant newt blastemal cells, and to transfect them in culture and in situ using a particle delivery system, has yielded new information about the action of retinoic acid on the blastema and the reversal of muscle differentiation during limb regeneration

引用

页码：169 / 173

页数：5

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