CEREBROSPINAL-FLUID AND SERUM NEOPTERIN LEVELS IN PATIENTS WITH LYME NEUROBORRELIOSIS

被引：31

作者：

DOTEVALL, L

FUCHS, D

REIBNEGGER, G

WACHTER, H

HAGBERG, L

机构：

[1] GOTHENBURG UNIV, DEPT INFECT DIS, S-41685 GOTHENBURG, SWEDEN

[2] UNIV INNSBRUCK, INST MED CHEM & BIOCHEM, A-6020 INNSBRUCK, AUSTRIA

来源：

INFECTION | 1990年 / 18卷 / 04期

关键词：

D O I：

10.1007/BF01643387

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Elevated (>3.0 nmol/l) cerebrospinal fluid neopterin concentrations were observed in 20 of 21 patients with Lyme neuroborreliosis compared with three of 11 control patients with headache, back pain or psychoneurotic disorders. Neopterin concentrations were correlated to mononuclear cell counts and protein concentrations in the cerebrospinal fluid (CSF). Following antibiotic treatment, CSF neopterin levels decreased. Serum neopterin levels were not significantly raised in patients with neuroborreliosis when compared to control subjects. Neopterin levels as well as cell count and protein concentration in the CSF are valuable inflammation markers of disease activity in Lyme neuroborreliosis. © 1990 MMV Medizin Verlag GmbH Müncher.

引用

页码：210 / 214

页数：5

共 17 条

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