ARACHIDONATE EPOXYGENASE - INHIBITORS AND METABOLITE ANALOGS

被引：20

作者：

FALCK, JR ^{[1
]}

MANNA, S ^{[1
]}

VIALA, J ^{[1
]}

SIDDHANTA, AK ^{[1
]}

MOUSTAKIS, CA ^{[1
]}

CAPDEVILA, J ^{[1
]}

机构：

[1] UNIV TEXAS,HLTH SCI CTR,DEPT BIOCHEM,DALLAS,TX 75235

来源：

TETRAHEDRON LETTERS | 1985年 / 26卷 / 19期

关键词：

D O I：

10.1016/S0040-4039(00)95076-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：2287 / 2290

页数：4

共 24 条

[1]

CAPDEVILA J, 1983, ENDOCRINOLOGY, V113, P421

[2] THE MECHANISTIC PLURALITY OF CYTOCHROME-P-450 AND ITS BIOLOGICAL RAMIFICATIONS [J].

CAPDEVILA, J ;

SAEKI, Y ;

FALCK, JR .

XENOBIOTICA, 1984, 14 (1-2) :105-118

[3] ARACHIDONIC-ACID EPOXIDATION - EPOXYEICOSATRIENOIC ACIDS ARE ENDOGENOUS CONSTITUENTS OF RAT-LIVER [J].

CAPDEVILA, J ;

PRAMANIK, B ;

NAPOLI, JL ;

MANNA, S ;

FALCK, JR .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1984, 231 (02) :511-517

[4] SYNTHESIS OF 3 POTENTIAL INHIBITORS OF THE BIOSYNTHESIS OF LEUKOTRIENES A-E [J].

COREY, EJ ;

PARK, H ;

BARTON, A ;

NII, Y .

TETRAHEDRON LETTERS, 1980, 21 (44) :4243-4246

[5] IRREVERSIBLE INHIBITION OF PROSTAGLANDIN AND LEUKOTRIENE BIOSYNTHESIS FROM ARACHIDONIC-ACID BY 11,12-DEHYDROARACHIDONIC AND 5,6-DEHYDROARACHIDONIC ACIDS, RESPECTIVELY [J].

COREY, EJ ;

MUNROE, JE .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1982, 104 (06) :1752-1754

[6] A SHORT 3-COMPONENT TOTAL SYNTHESIS OF 12-HYDROXYEICOSA-5,8,14(Z),10(E)-TETRAENOIC ACID (12-HETE) VIA THE CORRESPONDING KETONE [J].

COREY, EJ ;

KYLER, K ;

RAJU, N .

TETRAHEDRON LETTERS, 1984, 25 (45) :5115-5118

[7] SELECTIVE EPOXIDATION OF EICOSA-CIS-5,8,11,14-TETRAENOIC (ARACHIDONIC) ACID AND EICOSA-CIS-8,11,14-TRIENOIC ACID [J].

COREY, EJ ;

NIWA, H ;

FALCK, JR .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1979, 101 (06) :1586-1587

[8] CONTROLLED CHEMICAL SYNTHESIS OF THE ENZYMATICALLY PRODUCED EICOSANOIDS 11-HETE, 12-HETE, AND 15-HETE FROM ARACHIDONIC-ACID AND CONVERSION INTO THE CORRESPONDING HYDROPEROXIDES (HPETE) [J].

COREY, EJ ;

MARFAT, A ;

FALCK, JR ;

ALBRIGHT, JO .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1980, 102 (04) :1433-1435

[9] RATIONALLY DESIGNED, POTENT COMPETITIVE INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS [J].

COREY, EJ ;

CASHMAN, JR ;

KANTNER, SS ;

WRIGHT, SW .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1984, 106 (05) :1503-1504

[10] DOCOSAHEXAENOIC ACID IS A STRONG INHIBITOR OF PROSTAGLANDIN BUT NOT LEUKOTRIENE BIOSYNTHESIS [J].

COREY, EJ ;

SHIH, C ;

CASHMAN, JR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (12) :3581-3584

← 1 2 3 →