N-0164 INHIBITS GENERATION OF THROMBOXANE-A2-LIKE ACTIVITY FROM PROSTAGLANDIN ENDOPEROXIDES BY HUMAN PLATELET MICROSOMES

被引：53

作者：

KULKARNI, PS

EAKINS, KE

机构：

[1] COLUMBIA UNIV,COLL PHYS & SURG,DEPT OPHTHALMOL,NEW YORK,NY 10032

[2] COLUMBIA UNIV,COLL PHYS & SURG,DEPT PHARMACOL,NEW YORK,NY 10032

来源：

PROSTAGLANDINS | 1976年 / 12卷 / 03期

关键词：

D O I：

10.1016/0090-6980(76)90027-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：465 / 469

页数：5

共 11 条

[1]

BUNTING S, 1976, BRIT J PHARMACOL, V56, pP344

[2]

BUNTING S, 1976, JUL BRIT PHARM SOC D

[3]

EAKINS KE, IN PRESS

[4] PROSTAGLANDINS RELEASED BY SPLEEN [J].

GILMORE, N ;

VANE, JR ;

WYLLIE, JH .

NATURE, 1968, 218 (5147) :1135-&

[5] THROMBOXANES - NEW GROUP OF BIOLOGICALLY-ACTIVE COMPOUNDS DERIVED FROM PROSTAGLANDIN ENDOPEROXIDES [J].

HAMBERG, M ;

SVENSSON, J ;

SAMUELSSON, B .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1975, 72 (08) :2994-2998

[6]

LOWRY OH, 1951, J BIOL CHEM, V193, P265

[7] IDENTIFICATION OF AN ENZYME IN PLATELET MICROSOMES WHICH GENERATES THROMBOXANE-A-2 FROM PROSTAGLANDIN ENDOPEROXIDES [J].

NEEDLEMAN, P ;

MONCADA, S ;

BUNTING, S ;

VANE, JR ;

HAMBERG, M ;

SAMUELSSON, B .

NATURE, 1976, 261 (5561) :558-560

[8] RELEASE OF ADDITIONAL FACTORS IN ANAPHYLAXIS AND ITS ANTAGONISM BY ANTI-INFLAMMATORY DRUGS [J].

PIPER, PJ ;

VANE, JR .

NATURE, 1969, 223 (5201) :29-&

[9]

TAKEGUCHI C, 1971, BIOCHEMISTRY-US, V10, P2372

[10] INHIBITION OF PROSTAGLANDIN SYNTHESIS AS A MECHANISM OF ACTION FOR ASPIRIN-LIKE DRUGS [J].

VANE, JR .

NATURE-NEW BIOLOGY, 1971, 231 (25) :232-&

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